Benzonase Nuclease

Source

Recombinant gene engineering production, E. coli expression.

Product Introduction

Benzonase nuclease are nucleases from Serratia marcescens that have been genetically modified. They can degrade double-stranded, single-stranded, linear, and circular DNA and RNA, completely breaking down nucleic acids into 3-5 base-long 5′-monophosphate oligonucleotides. Because they can efficiently degrade any form of DNA and RNA, they are called “all-purpose nucleases.”

Product characteristics

  • Product appearance: colorless, transparent liquid
  • Activity: ≥250kU/ml
  • Purity: ≥99%
  • Bacterial endotoxin: ≤0.25EU/kU
  • Host DNA: ≤10ppm
  • Host protein: ≤50ppm
  • Microbial limits: in compliance
  • Molecular weight: ~28kD

Product features

  • Wide range of applications: high activity under high salt and low salt conditions.
  • Animal-free: produced by recombination, free of exogenous viral contamination, and no animal-derived raw materials are used in the production process.
  • Quality stability: batch production ensures continuous, stable batch production; small batch-to-batch differences and stable quality.
  • Complies with regulatory requirements: production equipment and environment comply with relevant regulations, and the production process fully complies with GMP guidelines.
  • Complete quality documents: relevant regulatory support documents are available upon customer request.

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